The immunogenicity of a bivalent mRNA vaccine with both ancestral and omicron BA.1 sequences elicited higher neutralization titers against BA.1 than did the ancestral strain–specific vaccine. Original Article Omicron Neutralization with Bivalent Vaccine Boost P.Participants who had received three doses of BNT162b2 vaccine received either a fourth dose or a bivalent vaccine containing BA.4–BA.5 mRNA the latter group had higher neutralization against omicron variants. Correspondence Bivalent Vaccine to Neutralize Omicron Variants J.In this study, effectiveness against hospitalization or death was 24.9% after a monovalent booster and 61.8% after a bivalent booster. Correspondence Effectiveness of Bivalent Covid-19 Boosters D.-Y.Whether the elicited antibodies protect against infection is unclear. Alves and Othersīoosters of adjuvanted NVX-CoV2373 protein vaccine led to increasing neutralizing titers of antibody specific for the ancestral strain and omicron variants. Correspondence Fourth Dose of SARS-CoV-2 Adjuvanted Protein Vaccine K.In a group of patients undergoing hemodialysis who had received four previous inoculations of SARS-CoV-2 vaccines, a fifth injection of a bivalent mRNA vaccine boosted serum neutralizing activity against omicron variants. Correspondence Bivalent SARS-CoV-2 Booster in Hemodialysis Patients L.Three 3-μg doses of the BNT162b2 vaccine were found to be immunogenic in children younger than 5 years of age and were associated with local reactions and systemic events that were similar to those seen in older children. Original Article Covid-19 Vaccine in Young Children F.M.Recently Published Vaccine Research and Review The most trusted, influential source of new medical knowledge and clinical best practices in the world. Information and tools for librarians about site license offerings. Valuable tools for building a rewarding career in health care. The authorized source of trusted medical research and education for the Chinese-language medical community. The most advanced way to teach, practice, and assess clinical reasoning skills. Information, resources, and support needed to approach rotations - and life as a resident. The most effective and engaging way for clinicians to learn, improve their practice, and prepare for board exams. NEW! Peer-reviewed journal featuring in-depth articles to accelerate the transformation of health care delivery.Ĭoncise summaries and expert physician commentary that busy clinicians need to enhance patient care. NEW! A digital journal for innovative original research and fresh, bold ideas in clinical trial design and clinical decision-making.
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